comparing the analgesic effect pregabalin and gabapentin as premedication in laparoscopic procedures
نویسندگان
چکیده
background: laparascopic surgery is associated with post operative pain .optimal pain treatment with minimal side effects is essential for early recovery and mobility in patients undergoing laparoscopic surgery .we compaired the analgesic effect pregabalin and gabapentin with different doses in this surgical procedurs.methods: in a randomized , double blind , ninety patients were allocated to either group a pregabalin 300mg , groupb gabapentin 600mg and groupc gabapentin 900mg .these were administered 1 h before operation .general anesthesia was performed .we collected data on pain intensity through visual analogue scale (vas) in recovery , 6 , 24 h after operation. consumption of supp diclofenac were recorded . p<0.05 was considered statistically significant.results: pregabalin 300 mg was significantly more effective in reducing post operative pain up to 24 hours following the surgery (p<0.001) . furthermore , the amount of analgesic consumption was less in the pregabalin group (p<0.001). consumption analgesic and vas were more than the other groups in patient who receive gabapentin 600 mg.conclusions: our finding showed that single dose of pregabalin 300mg oral is more effective than gabapatin on the management of postoperative pain following abdominal laparoscopic surgery. and pregabalin resulted in reduction in 24 h postoperative analgesic requirements.gabapentin 900mg decrease vas and consumption of analgesic significantly.
منابع مشابه
Effect of Pregabalin Premedication on the Requirement of Anesthetic and Analgesic Drugs in Laparoscopic Cholecystectomy: Randomized Comparison of Two Doses
BACKGROUND Preoperative medication has a vital role in anesthesia. Pregabalin (PG) is a newer drug of gabapentinoid class and is six times more potent than gabapentin. Our study was designed to evaluate the effect of PG as premedication on the perioperative anesthetic requirement and analgesia. MATERIALS AND METHODS The study was conducted on ninety patients of American Society of Anesthesiol...
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عنوان ژورنال:
بیهوشی و دردجلد ۲، شماره ۶، صفحات ۳۰-۳۷
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